The U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to two research projects funded by the California Institute for Regenerative Medicine (CIRM). RMAT is a fast-track designation that can help speed up the development, review, and potential approval of treatments for serious or life-threatening diseases. The first RMAT designation … Continue reading Two CIRM-funded research projects receive RMAT designation from FDA
Clinical Trials
How California is advancing our understanding of Alzheimer’s disease using stem cells
Over 14,000 people in Fresno County are living with Alzheimer's, and it’s estimated that more than 720,000 people are living with the brain disorder in California. That’s why the California Institute for Regenerative Medicine (CIRM)—a state of California agency dedicated to funding regenerative medicine research—joined the Alzheimer's Association Walk to End Alzheimer’s in Fresno/Madera to … Continue reading How California is advancing our understanding of Alzheimer’s disease using stem cells
CIRM Showcases Strategic Vision and New Initiatives at 7th Annual Alpha Clinics Network Symposium
Leveraging CIRM Infrastructure to Improve Accessibility Panel - From left to right: Noah Federman, MD (moderator), Catriona Jamieson, MD, PhD, Mehrdad Abedi, MD, Daniela Bota, MD, PhD, Thomas Buchanan, MD, Brian Fury, MS, Dhruv Sareen, PhD, and Taby Ahsan, PhD The California Institute for Regenerative Medicine (CIRM) recently sponsored the 7th Annual CIRM Alpha Clinics … Continue reading CIRM Showcases Strategic Vision and New Initiatives at 7th Annual Alpha Clinics Network Symposium
Stem Cell Awareness: What are stem cells and why research is important
Have you heard of stem cells but don't know what they are or why they are essential in medical research? In celebration of Stem Cell Awareness Day, the second Wednesday in October that is dedicated to educating about the importance of stem cells, the California Institute for Regenerative Medicine (CIRM) is providing this guide on … Continue reading Stem Cell Awareness: What are stem cells and why research is important
CIRM awards $8 million to Support Groundbreaking Gene Therapy for AML and MDS
Image source: Canva Around 20,000 Americans are affected by acute myeloid leukemia (AML) each year. AML is a type of cancer that originates in the bone marrow and rapidly enters the bloodstream. Additionally, many individuals are impacted by myelodysplastic syndromes (MDS), which are blood disorders that result in the improper formation or functioning of blood … Continue reading CIRM awards $8 million to Support Groundbreaking Gene Therapy for AML and MDS
CIRM awards $26 million to boost clinical trials for cancer, heart, and rare diseases
The California Institute for Regenerative Medicine (CIRM) is proud to announce the allocation of $26 million to support clinical research targeting a range of cancers, heart conditions, and rare diseases. This significant funding underscores CIRM’s commitment to advancing innovative stem cell and gene therapy-based treatments through all stages of clinical trial development. This latest round … Continue reading CIRM awards $26 million to boost clinical trials for cancer, heart, and rare diseases
Turning Hope into Reality: How a Genetic Therapy Helped Connor
Photo credit: n-Lorem Connor Dalby is a 15-year-old teenager who loves music and the beach, but his journey has been far from ordinary. Diagnosed with a rare mutation in the SCN2A gene, his life has been filled with challenges. From the time he was just a few weeks old, he had trouble sleeping and struggled … Continue reading Turning Hope into Reality: How a Genetic Therapy Helped Connor
Where Are They Now: Jake Javier
The California Institute for Regenerative Medicine (CIRM) in partnership with the University of Southern California (USC) recently hosted the 2024 CIRM Trainee Network Conference, which provided trainees from CIRM’s education and training programs an opportunity to engage with patient advocates and other professionals in the field. On the first day, Jake Javier took the stage … Continue reading Where Are They Now: Jake Javier
A Conversation with CEO Cory Nicholas on Neurona Therapeutics’ Recent RMAT Designation
At the California Institute for Regenerative Medicine (CIRM), we enjoy highlighting achievements that come out of the research we support. We recently sat down with Cory Nicholas, PhD, CEO and Co-Founder of Neurona Therapeutics, to discuss an important milestone for the clinical-stage company. Neurona recently received the FDA’s Regenerative Medicine Advanced Therapy (RMAT) designation for … Continue reading A Conversation with CEO Cory Nicholas on Neurona Therapeutics’ Recent RMAT Designation
Supporting a CAR-T cell trial for kidney cancer
Photo Credit: Allogene Therapeutics. Image of the ALLO-316 allogeneic CAR-T cell therapy. The California Institute for Regenerative Medicine (CIRM) awarded $15 million to Dr. John Le Gall and his team at Allogene Therapeutics. This funding will support the development of ALLO-316, an innovative anti-CD70 CAR-T cell product designed to treat metastatic clear cell renal cell … Continue reading Supporting a CAR-T cell trial for kidney cancer
The Stem Cellar 