20 Years of CIRM: From building the infrastructure to clinical trials 

Twenty years ago, Californians voted in favor of Proposition 71, which allocated $3 billion to support stem cell research and created the California Institute for Regenerative Medicine (CIRM). In 2020, Proposition 14 passed, providing an additional $5.5 billion. CIRM will reflect on the past two decades, highlighting early research that has evolved into potential therapies, … Continue reading 20 Years of CIRM: From building the infrastructure to clinical trials 

FDA Grants RMAT Designation to Luxa Biotechnology’s CIRM-funded Dry AMD Therapy 

Credit: Shutterstock The FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation for a project focused on vision loss that was funded in part by the California Institute for Regenerative Medicine (CIRM). This designation is given to highly promising regenerative medicine therapies that treat serious or life-threatening diseases with the goal of accelerating the path … Continue reading FDA Grants RMAT Designation to Luxa Biotechnology’s CIRM-funded Dry AMD Therapy 

Bridging the Gap: CIRM Tackles Cell and Gene Therapy Manufacturing Challenges

CIRM Manufacturing Network Symposium attendees. The California Institute for Regenerative Medicine (CIRM) is driving conversations and collaboration to address the manufacturing challenges of cell and gene therapies (CGT). CIRM hosted its inaugural Manufacturing Network Symposium in South San Francisco, bringing together more than 100 experts and stakeholders from the regenerative medicine field, including scientific leaders … Continue reading Bridging the Gap: CIRM Tackles Cell and Gene Therapy Manufacturing Challenges

Discovery Research into the Link Between Air Pollution and Autism

Infographic, provided by Dr. Liption and team, showcasing the link between air pollution and autism spectrum disorder As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our understanding of central nervous system (CNS) disorders. As part of this goal, CIRM … Continue reading Discovery Research into the Link Between Air Pollution and Autism

Using Genetic Sequencing and AI to Identify and Treat Schizophrenia

Top left to right: Tomasz Nowakowski, PhD, and Nevan Krogan, PhD Bottom left to right: Aparna Bhaduri, PhD; Matt State, PhD; Alice Ting, PhD; Trey Ideker, PhD; Willow Coyote-Maestas, PhD As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our … Continue reading Using Genetic Sequencing and AI to Identify and Treat Schizophrenia

CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism

From top left to right: Anne Bang, PhD; Carrie Bearden, PhD; Eugene Yeo, PhD; Jonathan Sebat, PhD Bottom left to right: Alysson Moutri, PhD; Lilia Iakoucheva, PhD; Sébastien Jacquemont; Trey Ideker, PhD  This blog is part of a series highlighting our ReMIND program and the researchers it’s supporting. To explore all features in the series, … Continue reading CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism

World AIDS Day at the 3rd Annual Timothy Ray Brown Community Cure Symposium

Event recap written by guest writer Jacqueline Hantgan, CIRM Sr. Outreach Advisor for Outreach and Advocacy December is HIV/AIDS Awareness Month. To commemorate this important event, CIRM recently supported the 3rd Annual Timothy Ray Brown Community Cure Symposium which took place at the Palm Springs Art Museum on World AIDS Day−December 1, 2024. It was … Continue reading World AIDS Day at the 3rd Annual Timothy Ray Brown Community Cure Symposium

The Stem Cellar’s Most Read Blogs of 2024

2024 was a significant year for the California Institute for Regenerative Medicine (CIRM). We reached many milestones, including celebrating our 20th anniversary and introducing our Strategic Allocation Framework (SAF) impact goals, all while continuing to fund innovative research and advancements in regenerative medicine.The Stem Cellar blog is where we share these stories and achievements, providing … Continue reading The Stem Cellar’s Most Read Blogs of 2024

Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder

Photo Courtesy of Andrea Fernandez de Soto Imagine a life where every time you step outside, everything in your environment poses a life-threatening risk. For children born with ADA-SCID (adenosine deaminase severe combined immunodeficiency), this is a reality. Their immune systems are so compromised that a common cold or a simple scrape on the knee … Continue reading Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder

A Step Forward in the Fight Against Advanced Kidney Cancer

Photo Courtesy: Allogene Therapeutics Metastatic renal cell carcinoma (RCC) is an advanced form of kidney cancer with few treatment options and a five-year survival rate of less than 17%. With funding support from CIRM, Allogene Therapeutics is developing ALLO-316, an allogeneic CAR-T cell therapy which targets CD70—a protein highly expressed on clear cell renal cell … Continue reading A Step Forward in the Fight Against Advanced Kidney Cancer