Leukocyte Adhesion Deficiency-I (LAD-I) is a rare pediatric disease caused by a mutation in a specific gene that causes low levels of a protein called CD18. Due to low levels of CD18, the adhesion of immune cells is affected, which negatively impacts the body’s ability to combat infections. Rocket Pharmaceuticals has announced positive results from … Continue reading CIRM funded trial for LAD-I announces positive results
Author: Yimy Villa
Miss the CIRM Grantee Meeting? Watch it online now!
Due to the ongoing coronavirus pandemic, CIRM converted its 2020 Grantee Meeting with UC Irvine & UC San Diego to a completely virtual format this year. Held on September 14 & 15, we brought together stem cell scientists and trainees that have received CIRM funding. In addition to the complex science, we also heard from … Continue reading Miss the CIRM Grantee Meeting? Watch it online now!
First patient in CIRM funded X-CGD trial gives back by working in patient care
Brenden Whittaker Brenden Whittaker was born with a rare genetic disorder called X-linked chronic granulomatous disease (X-CGD). This condition affects the immune system's ability to fight off common germs, specifically bacteria and fungi, and can result in infections that would only be mild for healthy people. Unfortunately for Brenden, he has suffered life-threatening infections that … Continue reading First patient in CIRM funded X-CGD trial gives back by working in patient care
CIRM Bridges program prepared student for research of a rare disease
Ian Blong, Ph.D., CIRM San Francisco State University Bridges to Stem Cell Research Alumnus Recently, The New York Times released a powerful article that tells the stories of four different families navigating the challenges of having a family member with a rare disease. One of these stories focused on Matt Wilsey, a tech entrepreneur and … Continue reading CIRM Bridges program prepared student for research of a rare disease
Stanford scientists link problems in nerve cells to schizophrenia
A spherical cluster of hundreds of thousands of brain cells cultured in a lab dish. A team of researchers studied such neuronal clusters to better understand schizophrenia.Image Credit: Pasca lab The neurological origins of mental illness continue to remain a mystery and along with it any potential treatments for these conditions. However, Dr. Sergiu Pasca … Continue reading Stanford scientists link problems in nerve cells to schizophrenia
Scientists create “drug-like” chemical that may inhibit pancreatic cancer stem cells
John R. Cashman, Ph.D. Supreme Court justice Ruth Bader Ginsburg's death this past week after battling stage 4 pancreatic cancer is a grim reminder of how aggressive the disease can be. In fact, pancreatic cancer will soon be the second leading cause of cancer-related death for individuals in the United States. Unfortunately, it is known … Continue reading Scientists create “drug-like” chemical that may inhibit pancreatic cancer stem cells
CIRM-funded treatment for cancer granted FDA breakthrough therapy designation
Mark Chao, M.D., Ph.D., cofounder of Forty Seven, Inc. and current VP of oncology clinical research at Gilead Sciences An antibody therapeutic, magrolimab, being tested for myelodysplastic syndrome (MDS), a group of cancers in which the bone marrow does not produce enough healthy blood cells , was granted breakthrough therapy designation with the Food and Drug Administration … Continue reading CIRM-funded treatment for cancer granted FDA breakthrough therapy designation
Graphite Bio launches and will prepare for clinical trial based on CIRM-funded research
Josh Lehrer, M.D., CEO of Graphite Bio This week saw the launch of the 45th startup company enabled by CIRM funding of translational research at California academic institutions. Graphite Bio officially launched with the help of $45M in funding led by bay area venture firms Versant Ventures and Samsara BioCapital to spinout a novel CRISPR … Continue reading Graphite Bio launches and will prepare for clinical trial based on CIRM-funded research
CIRM Funded Trial for Parkinson’s Treats First Patient
Dr. Krystof Bankiewicz Brain Neurotherapy Bio, Inc. (BNB) is pleased to announce the treatment of the first patient in its Parkinson’s gene therapy study. The CIRM-funded study, led by Dr. Krystof Bankiewicz, is one of the 64 clinical trials funded by the California state agency to date. Parkinson’s is a neurodegenerative movement disorder that affects … Continue reading CIRM Funded Trial for Parkinson’s Treats First Patient
CIRM-funded research aims to create a platform to test therapies for AMD
People with late stage age-related macular degeneration lose their central vision. So an image like the one on the left might appear to them as shown on the right. Credit: University of California - Santa Barbara Our vision is one of the most important senses that we use in our everyday lives. Whether its to … Continue reading CIRM-funded research aims to create a platform to test therapies for AMD
The Stem Cellar 