The Journey of a Homegrown Stem Cell Research All-Star

Nothing makes a professional sports team prouder than its homegrown talent. Training and mentoring a promising, hard-working athlete who eventually helps carry the team to a championship can lift the spirits of an entire city. Here at CIRM, we hold a similar sense of pride in Brian Fury, one of our own homegrown all-stars. Nearly … Continue reading The Journey of a Homegrown Stem Cell Research All-Star

Stem Cell Roundup: Rainbow Sherbet Fruit Fly Brains, a CRISPR/iPSC Mash-up and more

This week’s Round Up is all about the brain with some CRISPR and iPSCs sprinkled in: Our Cool Stem Cell Image of the Week comes from Columbia University’s Zuckerman Institute: This rainbow sherbet-colored scientific art is a microscopy image of a fruit fly nervous system in which brain cells were randomly labeled with different colors. … Continue reading Stem Cell Roundup: Rainbow Sherbet Fruit Fly Brains, a CRISPR/iPSC Mash-up and more

Patient’s Stage IV Cancer Held in Check by CIRM-Funded Clinical Trial [Video]

"In the last three scans, which I have every six weeks, they're showing that there is no mestastasis (invasive cancer) anywhere in my body. [The doctors] I guess were quite blown away because they didn't expect [the treatment] to be so quick or to be that complete."   Today we’re sharing the story of Tom … Continue reading Patient’s Stage IV Cancer Held in Check by CIRM-Funded Clinical Trial [Video]

Stem Cell RoundUp: CIRM Clinical Trial Updates & Mapping Human Brain

It was a very CIRMy news week on both the clinical trial and discovery research fronts. Here are some the highlights: Stanford cancer-fighting spinout to Genentech: 'Don't eat me' – San Francisco Business Times Ron Leuty, of the San Francisco Business Times, reported this week on not one, but two news releases from CIRM grantee … Continue reading Stem Cell RoundUp: CIRM Clinical Trial Updates & Mapping Human Brain

CHLA study explains how stem cells slow progression of kidney disorder

Not all stem cell-based therapies act by replacing diseased or damaged cells. Many treatments in clinical development rely on the injected stem cells releasing proteins which trigger the slow down or even reversal of damage caused by disease or injury. A new CIRM-funded study that’s developing a stem cell therapy for a rare kidney disease … Continue reading CHLA study explains how stem cells slow progression of kidney disorder

Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?

Skin stem cells specialize into new skin by sensing neighborhood crowding When embarking on a road trip, the GPS technology inside our smartphones helps us know where we are and how to get where we’re going. The stem cells buried in the deepest layers of our skin don’t have a GPS and yet, they do … Continue reading Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?

A new study suggests CRISPR gene editing therapies should be customized for each patient

You know a scientific advance is a big deal when it becomes the main premise and title of a Jennifer Lopez-produced TV drama. That’s the case for CRISPR, a revolutionary gene-editing technology that promises to yield treatments for a wide range of genetic diseases. In fact, clinical trials using the CRISPR method are already underway … Continue reading A new study suggests CRISPR gene editing therapies should be customized for each patient

CIRM interviews Lorenz Studer: 2017 recipient of the Ogawa-Yamanaka Stem Cell Prize [Video]

For eight long years, researchers who were trying to develop a stem cell-based therapy for Parkinson’s disease – an incurable movement disorder marked by uncontrollable shaking, body stiffness and difficulty walking – found themselves lost in the proverbial wilderness. In initial studies, rodent stem cells were successfully coaxed to specialize into dopamine-producing nerve cells, the … Continue reading CIRM interviews Lorenz Studer: 2017 recipient of the Ogawa-Yamanaka Stem Cell Prize [Video]

Comparing two cellular reprogramming methods from one donor’s cells yields good news for iPSCs

In 2012, a mere six years after his discovery of induced pluripotent stem cells (iPSCs), Shinya Yamanaka was awarded the Nobel Prize in Medicine. Many Nobel winners aren’t recognized until decades after their initial groundbreaking studies. That goes to show you the importance of Yamanaka’s technique, which can reprogram a person’s cells, for example skin … Continue reading Comparing two cellular reprogramming methods from one donor’s cells yields good news for iPSCs

Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies

When the immune system comes up as a topic in everyday conversation, it’s usually related to fighting off a cold or flu. While our immune cells certainly do detect and neutralize invading bacteria and viruses, they also play a critical role in killing abnormal, cancerous cells from within our bodies. “Don’t Eat Me” Signal 101 … Continue reading Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies