CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia

Imagine you’ve just stopped your car at the top of the steepest street in San Francisco. Now, if want to stay at the top of the hill you’re going to need to keep your foot on the brakes. Let go and you’ll start rolling down. Fast. Conceptually, similar decision points happen in human development. A … Continue reading CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia

Stem cell stories that caught our eye: menstrual cycle on a chip, iPS cells from urine, Alpha Stem Cell Clinic Symposium videos

Say hello to EVATAR, a mini female reproductive system on a 3D chip. (Karen Ring) I was listening to the radio this week in my car and caught snippets of a conversation that mentioned the word “Evatar”. Having tuned in halfway through the story, naturally I thought that the reporters were talking about James Cameron’s … Continue reading Stem cell stories that caught our eye: menstrual cycle on a chip, iPS cells from urine, Alpha Stem Cell Clinic Symposium videos

Bye Bye bubble baby disease: promising results from stem cell gene therapy trial for SCID

You don’t need to analyze any data to know for yourself that Evangelina Vaccaro’s experimental stem cell therapy has cured her of a devastating, often fatal disease of the immune system. All you have to do is look at a photo or video of her to see that she’s now a happy, healthy 5-year-old with a … Continue reading Bye Bye bubble baby disease: promising results from stem cell gene therapy trial for SCID

Stem cell stories that caught our eye: spinal cord injury trial update, blood stem cells in lungs, and using parsley for stem cell therapies

More good news on a CIRM-funded trial for spinal cord injury. The results are now in for Asterias Biotherapeutics’ Phase 1/2a clinical trial testing a stem cell-based therapy for patients with spinal cord injury. They reported earlier this week that six out of six patients treated with 10 million AST-OPC1 cells, which are a type … Continue reading Stem cell stories that caught our eye: spinal cord injury trial update, blood stem cells in lungs, and using parsley for stem cell therapies

A stem cell clinical trial for blindness: watch Rosie’s story

https://youtu.be/oH4vlVWl6WY Everything we do at CIRM is laser-focused on our mission: to accelerate stem cell treatments for patients with unmet medical needs. So, you might imagine what a thrill it is to meet the people who could be helped by the stem cell research we fund. People like Rosie Barrero who suffers from Retinitis Pigmentosa … Continue reading A stem cell clinical trial for blindness: watch Rosie’s story

A horse, stem cells and an inspiring comeback story that may revolutionize tendon repair

Everyone loves a good comeback story. Probably because it leaves us feeling inspired and full of hope. But the comeback story about a horse named Dream Alliance may do more than that: his experience promises to help people with Achilles tendon injuries get fully healed and back on their feet more quickly. Dream Alliance was … Continue reading A horse, stem cells and an inspiring comeback story that may revolutionize tendon repair

3D printing blood vessels: a key step to solving the organ donor crisis

About 120,000 people in the U.S. are on a waiting list for an organ donation and every day 22 of those people will die because there aren’t enough available organs. To overcome this organ donor crisis, bioengineers are working hard to develop 3D printing technologies that can construct tissues and organs from scratch by using … Continue reading 3D printing blood vessels: a key step to solving the organ donor crisis

Stem cell stories that caught our eye: building an embryo and reviving old blood stem cells

Building an embryo in the lab from stem cells The human body has been studied for centuries yet little is known about the first 14 days of human development when the fertilized embryo implants into the mother’s uterus and begins to divide and grow. Being able to precisely examine this critical time window may help … Continue reading Stem cell stories that caught our eye: building an embryo and reviving old blood stem cells

Reducing animal testing with stem cells and electronic petri dishes

Though the celebrities at Sunday’s Academy Awards worked hard to sport unique clothing and hair styles, I bet many had something in common: Botox injections. Botox, an FDA-approved, marketed form of Botulism neurotoxin, is well known for its wrinkle reducing effects. The neurotoxin’s other claim to fame is the fact that it’s the most lethal, … Continue reading Reducing animal testing with stem cells and electronic petri dishes

Stem cells stories that caught our eye: switching cell ID to treat diabetes, AI predicts cell fate, stem cell ALS therapy for Canada

Treating diabetes by changing a cell’s identity. Stem cells are an ideal therapy strategy for treating type 1 diabetes. That’s because the disease is caused by the loss of a very specific cell type: the insulin-producing beta cell in the pancreas. So, several groups are developing treatments that aim to replace the lost cells by transplanting … Continue reading Stem cells stories that caught our eye: switching cell ID to treat diabetes, AI predicts cell fate, stem cell ALS therapy for Canada