California agency invests $4 million in stem cell treatment for Parkinson’s Disease

The California Institute for Regenerative Medicine (CIRM) is investing $4 million in a late-stage preclinical project by Ryne Bio aiming to improve treatment for Idiopathic Parkinson's disease (PD). PD is characterized by a loss of dopamine producing neurons that result in motor symptoms, such as dyskinesias (involuntary, erratic, writhing movements of the face, arms, legs … Continue reading California agency invests $4 million in stem cell treatment for Parkinson’s Disease

Funding development of a vaccine for acute myelogenous leukemia (AML)

Dr. Karin Gaensler. Photo credit: Steve Babuljak/UCSF Adult acute myelogenous leukemia—also known as acute myeloid leukemia (AML)—is a blood cancer in which the bone marrow makes a large number of abnormal blood cells.  About 20,000 new cases of AML are diagnosed each year in the US with a 5-year survival rate of around 29%. In … Continue reading Funding development of a vaccine for acute myelogenous leukemia (AML)

The Most Read Stem Cellar Blog Posts of 2022

This year was a momentous one for the California Institute for Regenerative Medicine (CIRM). You can read some of our achievements in our 2021-2022 annual report.   As always, we shared our most exciting updates and newsworthy stories—topics ranging from stem cell research to diversity in science—right here on The Stem Cellar. More than 100,000 blog … Continue reading The Most Read Stem Cellar Blog Posts of 2022

Finding a treatment for Tay-Sachs disease

The California Institute for Regenerative Medicine (CIRM) has awarded $4,048,253 to Dr. Joseph Anderson and his team at UC Davis to develop a blood stem cell gene therapy for the treatment of Tay-Sachs disease.   Tay-Sachs disease is a rare genetic disorder where a deficiency in the Hex A gene results in excessive accumulation of … Continue reading Finding a treatment for Tay-Sachs disease

CIRM funds clinical trial to make cancer therapy safer, less toxic

Blood stem cell transplantation following high dose chemotherapy is standard of care and potentially curative for aggressive forms of lymphoma. However, this treatment regimen is limited by severe toxicity and life-threatening complications due to delayed recovery of the blood system and vascular related damage of multiple organs. Today the governing Board of the California Institute … Continue reading CIRM funds clinical trial to make cancer therapy safer, less toxic

Three women with ties to CIRM featured in 2022 Women in Biopharma list 

Endpoints News released its 2022 Women in Biopharma list, which recognizes 20 of the top women leading biopharma research and development (R&D).   This year, the publication received more than 500 entries and selected 20 women “who have blazed trails and are still promising to reshape biopharma R&D for years to come.”  There are many amazing … Continue reading Three women with ties to CIRM featured in 2022 Women in Biopharma list 

High school SPARK intern presents stem cell research to academic audience 

Earlier this year, CIRM welcomed many energetic and enthusiastic high school students at the 2022 SPARK Program annual conference in Oakland. The SPARK program is one of the California Institute for Regenerative Medicine’s (CIRM) many programs dedicated to building a diverse and highly-skilled workforce to support the growing regenerative medicine economy right here in California.    … Continue reading High school SPARK intern presents stem cell research to academic audience 

Tratando malformaciones congénitas antes del nacimiento 

El bebé, Tobi recibió un tratamiento de células madre, financiado por el CIRM, mientras aún estaba en el útero. To read this blog in English, click here. Michelle y Jeff se llenaron de felicidad cuando se enteraron de que iban a tener un bebé.   Luego, un examen de ultrasonido a las 20 semanas del embarazo … Continue reading Tratando malformaciones congénitas antes del nacimiento 

Study could pave the way in reducing decline in muscle strength as people age 

A study by Stanford Medicine researchers in older mice may lead to treatments that help seniors regain muscle strength lost to aging. Muscle stem cells—which are activated in response to muscle injury to regenerate damaged muscle tissue—lose their potency with age. A study from the National Health and Nutrition Examination Survey showed that five percent … Continue reading Study could pave the way in reducing decline in muscle strength as people age 

Apply Now for New Manufacturing Funding Opportunity

The California Institute for Regenerative Medicine (CIRM) has set goals through its five-year strategic plan to continue to deliver the full potential of regenerative medicine to the people of California and around the world.  One of those goals is to overcome manufacturing hurdles for the delivery of regenerative medicine therapies by building a public-private manufacturing … Continue reading Apply Now for New Manufacturing Funding Opportunity