The bootcamp helping in the fight against rare diseases

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Emil Kakkis at the Rare Entrepreneur Bootcamp Imagine you or someone you love is diagnosed with a rare disease and then told, “There is no cure, there are no treatments and because it’s so rare no one is even doing any research into developing a … Continue reading The bootcamp helping in the fight against rare diseases

New funding opportunity in CIRM’s Discovery stage programs: the Foundation Awards 

Applications for CIRM’s new Discovery stage Foundation Awards (DISC 0) are due May 26th, 2022 by 2:00 PM PDT.  The California Institute for Regenerative Medicine (CIRM) is pleased to announce a brand new funding opportunity within our Discovery stage programs, the DISC 0 Foundation Awards which will support rigorous studies addressing critical basic knowledge gaps in the … Continue reading New funding opportunity in CIRM’s Discovery stage programs: the Foundation Awards 

Celebrating National DNA Day Together

DNA provides the code of life for nearly all living organisms. So, it’s no wonder that scientists have been studying DNA and the human genome (complete set of DNA) for decades. In April 1953, James Watson and Francis Crick, in collaboration with Rosalind Franklin, first described the structure of DNA as a double helix. In … Continue reading Celebrating National DNA Day Together

Stem cell agency invests in therapy using killer cells to target colorectal, breast and ovarian cancers

While there have been some encouraging advances in treating cancer in recent decades, there are still many cancers that either resist treatment or recur after treatment. Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved investing in a therapy targeting some of these hard-to-treat tumors. BioEclipse Therapeutics Inc. was awarded nearly … Continue reading Stem cell agency invests in therapy using killer cells to target colorectal, breast and ovarian cancers

How two women are fighting back against Lou Gehrig’s disease

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Mary Ann Wittenberg (left) and Nadia Sethi Lou Gehrig's disease, or ALS, is a nasty degenerative condition that destroys the brain cells controlling movement. People with ALS suffer a progressive loss of ability to walk, talk, eat and breathe. The average life expectancy for someone diagnosed … Continue reading How two women are fighting back against Lou Gehrig’s disease

UCLA-led team creates first comprehensive map of human blood stem cell development

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Human blood stem cells emerging from specialized endothelial cells in the wall of an embryonic aorta. UCLA scientists’ confirmation of this process clarifies a longstanding controversy about the stem cells’ cellular origin. Image Credit: Hanna Mikkola Lab/UCLA, Katja Schenke-Layland Lab/University of Tübingen, Nature California researchers from … Continue reading UCLA-led team creates first comprehensive map of human blood stem cell development

Turning back the clock to make old skin cells young again

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Diljeet Gill, photo courtesy Babraham Institute, Cambridge UK Sometimes when I am giving public presentations people ask if stem cells are good for the face. I always say that if stem cells could help improve people’s faces would I look like this. It’s a line … Continue reading Turning back the clock to make old skin cells young again

Expanding CIRM’s Alpha Clinics Network to deliver transformative regenerative medicine treatments 

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Almost every day, we hear new reports from the thousands of regenerative medicine clinical trials globally sponsored by hundreds of companies and academic researchers. The California Institute for Regenerative Medicine (CIRM) is a leader in this space supporting some of the most advanced cell and gene … Continue reading Expanding CIRM’s Alpha Clinics Network to deliver transformative regenerative medicine treatments 

Recovery from muscle loss injuries hindered by immune cell conflicts

During a game in 2018, Alex Smith suffered a compound fracture that broke both the tibia and fibula in his right leg. The gruesome injury aside, the former 49ers quarterback soon developed life-threatening necrotizing fasciitis — a rare bacterial infection — that resulted in sepsis and required him to undergo 17 surgeries. In a battle to save his … Continue reading Recovery from muscle loss injuries hindered by immune cell conflicts

Reversing hearing loss through regenerative medicine

These images show cellular regeneration, in pink, in a preclinical model of sensorineural hearing loss. The control is on the left and the right has been treated. Image: Hinton AS, Yang-Hood A, Schrader AD, Loose C, Ohlemiller KK, McLean WJ. Most of us know someone affected by hearing loss, but we may not fully realize … Continue reading Reversing hearing loss through regenerative medicine