Stem cells can screen drugs for sometimes-lethal side effects

CIRM grantee Bruce Conklin recently spoke at the California Academy of Sciences about using reprogrammed skin cells (so-called iPS cells) to test drugs for lethal side effects in the heart. You can see a 4 minute excerpt of that talk here. One of the most common reasons for a drug to fail clinical trials is … Continue reading Stem cells can screen drugs for sometimes-lethal side effects

Jonathan Thomas discusses plans to extend CIRM’s benefits to California

Jonathan Thomas is chair of the CIRM governing board. This week CIRM delivered a document to the governor, state controller, state treasurer and state legislature describing how CIRM intends to ensure that its mission extends beyond the $3 billion authorized by proposition 71. Based on our current estimate, we expect to issue the final grants … Continue reading Jonathan Thomas discusses plans to extend CIRM’s benefits to California

Francis collins on stem cells, disease modeling, and finding therapies

Former CIRM board member John Reed, Professor and CEO of Sanford-Burnham Medical Research Institute, recently interviewed Francis Collins for Medscape one-on-one. Collins is Director of the National Institutes of Health (NIH), and a vocal supporter of funding stem cell research.The interview covers Collins’ own beginnings in science and advances over the last decade in genome … Continue reading Francis collins on stem cells, disease modeling, and finding therapies

CIRM: the audacious vision is still possible

This weekend the Sacramento Bee ran an opinion piece about the future of stem cell research in general, and CIRM’s role in particular. The story was interesting in its focus on the process of developing and funding a new therapy—which can be long and arduous, and it only getting more so.David Lesher wrote:Those who speculate … Continue reading CIRM: the audacious vision is still possible

Valentine’s Day Stem Cell Wish: Mending Broken Hearts

At CIRM, our Valentine’s Day present came in the form of a paper published in The Lancet by grantee Eduardo Marban. He showed the results of a study finding that stem cells taken from the heart can help reduce scar tissue after a heart attack.Marban, who is director of the Cedars-Sinai Heart Institute, spoke to … Continue reading Valentine’s Day Stem Cell Wish: Mending Broken Hearts

Personalized medicine may help treat childhood brain tumors

Cerebellar stem cells engineered to express Myc and mutant p53 (shown here) give rise to aggressive tumors that resemble a particularly malignant form of human medulloblastoma, providing a new model that will help scientists develop more effective therapies for this disease.When CIRM grantee Robert Wechsler-Reya received a Leadership Award to lure him from Duke University … Continue reading Personalized medicine may help treat childhood brain tumors

CIRM grantee Sheng Ding among the Bay Area’s 40 leaders under 40

Sheng Ding of the J. David Gladstone Institutes in San Francisco has been making a name for himself in stem cell circles. Now he’s being recognized in the business community, earning a place on the San Francisco Business Times’ 2012 40 under 40 roster. Ding has a New Faculty Award and a New Cell Lines … Continue reading CIRM grantee Sheng Ding among the Bay Area’s 40 leaders under 40

CIRM Creativity Award student semifinalist in national science competition

Last summer CIRM piloted a high school internship program that brought students, many from socioeconomically deprived backgrounds, into stem cell research labs. One of those students went on to be a semifinalist in both the Siemens National Science Competition and the Intel STS National Talent Search. Ryan Chow of Leland High School in San Jose, … Continue reading CIRM Creativity Award student semifinalist in national science competition

Poll says CIRM initiatives advance stem cell science

According to a poll held by Genetic Engineering and Biotechnology News, 63.1% of respondents said that CIRM initiatives had been either very helpful or somewhat helpful in advancing stem cell science. We couldn’t agree more. And for those 22.6% who said that CIRM was not very helpful, we encourage them to visit our website for … Continue reading Poll says CIRM initiatives advance stem cell science

Stem cells help build bones, could one day treat osteoporosis

A team of researchers at the University California, Davis have published work showing a way of stimulating the body’s stem cells to build more bone. In mice with a version of osteoporosis, the approach resulted in animals with bulkier bones in the leg and spine, and those bones were also stronger compared to those of … Continue reading Stem cells help build bones, could one day treat osteoporosis