Scientists Send Rodents to Space; Test New Therapy to Prevent Bone Loss

In just a few months, 40 very special rodents will embark upon the journey of a lifetime. Today UCLA scientists are announcing the start of a project that will test a new therapy that has the potential to slow, halt or even reverse bone loss due to disease or injury. With grant funding from the … Continue reading Scientists Send Rodents to Space; Test New Therapy to Prevent Bone Loss

UC Davis Surgeons Begin Clinical Trial that Tests New Way to Deliver Stem Cells; Heal Bone Fractures

Each year, approximately 8.9 million people worldwide will suffer a bone fracture. Many of these fractures heal with the help of traditional methods, but for some, the road to recovery is far more difficult. After exhausting traditional treatments—such as surgically implanted pins or plates, bed rest and injections to spur bone growth—these patients can undergo … Continue reading UC Davis Surgeons Begin Clinical Trial that Tests New Way to Deliver Stem Cells; Heal Bone Fractures

In living color: new imaging technique tracks traveling stem cells

Before blood stem cells can mature, before they can grow and multiply into the red blood cells that feed our organs, or the white blood cells that protect us from pathogens, they must go on a journey. This journey, which takes place in the developing embryo, moves blood stem cells from their place of origin … Continue reading In living color: new imaging technique tracks traveling stem cells

2015 Golden Globes shines light on Alzheimer’s and ALS with acting awards

In between the one-liners, surprise presenters and bottomless champagne, something remarkable happened at last night’s 72nd Golden Globe Awards. 26 awards were given last night to the best in film and television. But two in particular were especially meaningful. I am referring, of course, to Julianne Moore and Eddie Redmayne, who each took home awards … Continue reading 2015 Golden Globes shines light on Alzheimer’s and ALS with acting awards

Multitasking molecule repairs damaged nerve cells, scientists discover in ‘stunning’ research breakthrough

Every molecule in the body has a job to do—everything from maintaining healthy cell functions to removing dead or decaying cells requires a coordinated series of molecular switches to complete. There’s a lot we know about what these molecules do, but even more that we are still discovering. And as reported in a pair of … Continue reading Multitasking molecule repairs damaged nerve cells, scientists discover in ‘stunning’ research breakthrough

Scientists identify gene that causes good protein to turn bad

There exists a protein that, most of the time, helps keep the growth of cancer cells in check. But every so often it does the opposite—with potentially deadly consequences. But now, researchers have discovered precisely why this protein, known as TGF-beta, can perform such an abrupt about-face. The results, published today in the journal Science … Continue reading Scientists identify gene that causes good protein to turn bad

CIRM-funded scientists track the steps that take an adult cell back in time

The ability to transform an adult cell back into a stem cell has been heralded as one of the greatest achievements of the 21st century. Scientists have lauded this discovery, made by Nobel Prize-winning scientist Shinya Yamanaka, as a game changer for the future of medicine. Despite this extraordinary advance, the method remains inefficient. And … Continue reading CIRM-funded scientists track the steps that take an adult cell back in time

Stem Cell Stories that Caught Your Eye: The Most Popular Stem Cellar Stories of 2014

2014 marked an extraordinary year for regenerative medicine and for CIRM. We welcomed a new president, several of our research programs have moved into clinical trials—and our goal of accelerating treatments for patients in need is within our grasp. As we look back we’d like to revisit The Stem Cellar’s ten most popular stories of … Continue reading Stem Cell Stories that Caught Your Eye: The Most Popular Stem Cellar Stories of 2014

Key stem cell gene controlled from afar, Canadian scientists discover

Embryonic stem cells can, by definition, mature into any cell type in the body. They are able to maintain this state of so-called pluripotency with the help of a gene called Sox2. And now, researchers at the University of Toronto (U of T) have discovered the unseen force that controls it. These findings, reported in … Continue reading Key stem cell gene controlled from afar, Canadian scientists discover

A time to kill, a time to heal: cells linked to aging also help heal wounds

Senescent cells, so called because of the role they play in the aging process, have acquired a bit of a bad reputation. Yet new research from the Buck Institute suggests that these cells may not be so bad after all. Reporting in today's issue of Developmental Cell, Buck Institute scientists have found that, while senescent … Continue reading A time to kill, a time to heal: cells linked to aging also help heal wounds