CIRM invests $50 million in clinical research, including trial for vision loss

The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, today awarded $50.1 million to fund clinical-stage research projects aimed at advancing stem cell and gene therapy treatments for a variety conditions ranging from neurodegenerative diseases and blood cancers to HIV/AIDS.  The awards will support six projects in the Agency’s … Continue reading CIRM invests $50 million in clinical research, including trial for vision loss

Novartis acquisition validates CIRM’s impact on cystinosis treatment

Dr. Stephanie Cherqui The future looks brighter for cystinosis patients and their families.   As one of 7,000 rare diseases, cystinosis causes an abnormal build-up of the amino acid cystine that can lead to organ failure and premature death. With little to no treatment options, children and young adults primarily affected by the condition often have … Continue reading Novartis acquisition validates CIRM’s impact on cystinosis treatment

How CIRM-funded research is bringing a lifesaving gene therapy to a 5-year-old

For her first year of life, Seersha Sulack stayed mostly in her bedroom because something as simple as a common cold could have killed her. The five-year-old was born with ADA-SCID, a condition so rare that only eight babies a year are born with it in the United States.  Now, thanks to the work of … Continue reading How CIRM-funded research is bringing a lifesaving gene therapy to a 5-year-old

#Take6ForPD: CIRM Board member David Higgins shares why Parkinson’s awareness matters

April is Parkinson’s Awareness Month and the California Institute for Regenerative Medicine (CIRM) is joining the campaign to #Take6ForPD—take 6 minutes to raise Parkinson’s awareness and highlight our commitment to funding research for the disease.  In addition to highlighting our commitment to funding research for Parkinson's Disease, we're also giving patients and patient advocates the opportunity to … Continue reading #Take6ForPD: CIRM Board member David Higgins shares why Parkinson’s awareness matters

CIRM commits $60 million for Parkinson’s research, joins #Take6ForPD awareness campaign 

April is Parkinson’s Awareness Month and the California Institute for Regenerative Medicine (CIRM) is joining the campaign to #Take6ForPD—take 6 minutes to raise Parkinson’s awareness and highlight our commitment to funding research for the disease.  What is Parkinson’s Disease?  Parkinson's disease (PD) is a neurodegenerative disease that affects nearly 1 million people in the United States … Continue reading CIRM commits $60 million for Parkinson’s research, joins #Take6ForPD awareness campaign 

Join the movement to fight rare diseases

Tomorrow, February 28th, is Rare Disease Day. It’s a day to remind ourselves of the millions of people, and their families, struggling with these diseases. These conditions are also called orphan diseases because, in many cases, drug companies were not interested in adopting them to develop treatments. Here at the California Institute for Regenerative Medicine (CIRM), we … Continue reading Join the movement to fight rare diseases

Investing in stem cell and gene therapy treatments for HIV

A recent article in Nature shared the news about a 53-year-old man in Germany who was declared free of HIV after receiving virus-resistant cells.  The man—referred to as the “Düsseldorf patient”—was diagnosed with acute myeloid leukemia and underwent a stem cell transplant in 2013 that replaced his bone marrow cells with HIV-resistant stem cells from … Continue reading Investing in stem cell and gene therapy treatments for HIV

CIRM board member Ysabel Duron appointed to National Cancer Advisory Board by President Biden

Ysabel Duron is an award-winning journalist, patient advocate, cancer survivor and board member of the California Institute for Regenerative Medicine (CIRM).  Her list of achievements continues to grow, as President Biden has appointed Duron to National Cancer Advisory Board (NCAB), which plays an important role in setting the course for the national cancer research program.  … Continue reading CIRM board member Ysabel Duron appointed to National Cancer Advisory Board by President Biden

California agency invests $4 million in stem cell treatment for Parkinson’s Disease

The California Institute for Regenerative Medicine (CIRM) is investing $4 million in a late-stage preclinical project by Ryne Bio aiming to improve treatment for Idiopathic Parkinson's disease (PD). PD is characterized by a loss of dopamine producing neurons that result in motor symptoms, such as dyskinesias (involuntary, erratic, writhing movements of the face, arms, legs … Continue reading California agency invests $4 million in stem cell treatment for Parkinson’s Disease

Investing in CAR T-cell therapy to treat cancer

Photo credit: UC Regents  The California Institute for Regenerative Medicine (CIRM) is investing $4 million to support Dr. William Murphy and UC Davis researchers to develop and test a chimeric antigen receptor (CAR) T-cell therapy to treat various B-cell malignancies, ranging from lymphomas to leukemias.  In this Q&A—courtesy of UC Davis Health—Dr. Murphy discusses the importance of T-cell therapy and its implications … Continue reading Investing in CAR T-cell therapy to treat cancer