Photo credit: n-Lorem Connor Dalby is a 15-year-old teenager who loves music and the beach, but his journey has been far from ordinary. Diagnosed with a rare mutation in the SCN2A gene, his life has been filled with challenges. From the time he was just a few weeks old, he had trouble sleeping and struggled … Continue reading Turning Hope into Reality: How a Genetic Therapy Helped Connor
Clinical Trials
Where Are They Now: Jake Javier
The California Institute for Regenerative Medicine (CIRM) in partnership with the University of Southern California (USC) recently hosted the 2024 CIRM Trainee Network Conference, which provided trainees from CIRM’s education and training programs an opportunity to engage with patient advocates and other professionals in the field. On the first day, Jake Javier took the stage … Continue reading Where Are They Now: Jake Javier
A Conversation with CEO Cory Nicholas on Neurona Therapeutics’ Recent RMAT Designation
At the California Institute for Regenerative Medicine (CIRM), we enjoy highlighting achievements that come out of the research we support. We recently sat down with Cory Nicholas, PhD, CEO and Co-Founder of Neurona Therapeutics, to discuss an important milestone for the clinical-stage company. Neurona recently received the FDA’s Regenerative Medicine Advanced Therapy (RMAT) designation for … Continue reading A Conversation with CEO Cory Nicholas on Neurona Therapeutics’ Recent RMAT Designation
Supporting a CAR-T cell trial for kidney cancer
Photo Credit: Allogene Therapeutics. Image of the ALLO-316 allogeneic CAR-T cell therapy. The California Institute for Regenerative Medicine (CIRM) awarded $15 million to Dr. John Le Gall and his team at Allogene Therapeutics. This funding will support the development of ALLO-316, an innovative anti-CD70 CAR-T cell product designed to treat metastatic clear cell renal cell … Continue reading Supporting a CAR-T cell trial for kidney cancer
CIRM’s $31 million boost for cancer and eye disease research
The California Institute for Regenerative Medicine (CIRM) recently approved nearly $31 million in funding, further cementing our commitment to advancing the field of regenerative medicine. This substantial investment aims to drive clinical research targeting various cancers and eye diseases. CIRM’s dedication to fostering innovative treatments is demonstrated through its clinical program, which funds eligible stem … Continue reading CIRM’s $31 million boost for cancer and eye disease research
Tackling sickle cell disease from within
Photo Credit: Jaquell Chandler Evie Junior was born with sickle cell disease, a life-threatening condition that affects around 100,000 Americans, most of them Black and Latino. People with sickle cell disease have blood cells that are shaped like a hook (or sickle) rather than smooth and round, which can create clogs, causing intense pain, organ … Continue reading Tackling sickle cell disease from within
CIRM awards $25 million for discovery and clinical research, infrastructure programs
Stock image of a researcher The California Institute for Regenerative Medicine (CIRM) has recently approved awarding $25 million to fund multiple projects across discovery research, clinical research, and infrastructure programs.This funding will support 11 projects under CIRM's Foundation Awards Program, which aims to drive rigorous studies addressing critical basic knowledge gaps in the biology of … Continue reading CIRM awards $25 million for discovery and clinical research, infrastructure programs
CIRM Funds Clinical Research for Individualized Stem Cell Treatment for Parkinson’s
Stock image of Parkinson's disease nerve cells. The California Institute for Regenerative Medicine (CIRM) has approved an $8 million award to Aspen Neuroscience to advance an investigational stem cell-derived dopaminergic neuron replacement therapy for Parkinson’s disease (PD). This individualized potential therapy is being explored in a first-in-human Phase 1/2a clinical trial for patients with moderate … Continue reading CIRM Funds Clinical Research for Individualized Stem Cell Treatment for Parkinson’s
CIRM celebrates landmark 100+ clinical trial awards
Photo credit: Barbara Ries for UCSF, Jaquell Chandler, and OHSU/Christine Torres Hicks The California Institute for Regenerative Medicine (CIRM), California’s Stem Cell Agency and the world’s largest institution dedicated to regenerative medicine reached a milestone when it approved funding for its 100th clinical trial. At the February Independent Citizens’ Oversight Committee (ICOC) meeting, the board … Continue reading CIRM celebrates landmark 100+ clinical trial awards
CIRM awards more than $56 million for clinical research aimed at treating Parkinson’s disease, autoimmune conditions and a variety of cancers
The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, awarded $56 million to fund various clinical research aimed at treating Parkinson’s disease, autoimmune conditions and a variety of cancers. The awards will support seven projects—five clinical trials and two preclinical projects—in the Agency’s clinical program which provides funding for … Continue reading CIRM awards more than $56 million for clinical research aimed at treating Parkinson’s disease, autoimmune conditions and a variety of cancers
The Stem Cellar 