Researchers at the Salk Institute for Biological Sciences have grown embryonic stem cells into the motor neurons and support cells that underlie amyotrophic lateral sclerosis (ALS). Also known as Lou Gherig’s Disease, ALS has no cure and no effective treatment. In this disease, the motor neurons slowly degenerate leaving a person paralyzed. Why the neurons … Continue reading Embryonic Stem Cells Generate Model for ALS
Author: cirmweb
Origin of blood stem cells found to be in the lining of blood vessels
Researchers at UC, Los Angeles have found that blood-forming stem cells in mice have their origins in the endothelial cells that line blood vessels during mid-gestation. These cells eventually move to the bone marrow where they generate all the cells of the blood system throughout life. Researchers have long known that blood-forming stem cells arise … Continue reading Origin of blood stem cells found to be in the lining of blood vessels
Genetic Factor Enables Immature Cells to Form Normal Heart Tissue
Researchers at the Gladstone Institute for Cardiovascular Disease found a genetic factor that helps in the earliest stages of heart development as the primitive tube loops around on itself and forms the separate chambers. This factor -- a short relative of DNA called microRNA -- has an identical counterpart in humans, leading the researchers to … Continue reading Genetic Factor Enables Immature Cells to Form Normal Heart Tissue
Protein found to direct embryonic stem cells as they mature
Researchers at the Stanford University School of Medicine have found that clusters of embryonic stem cells in a lab dish share some unexpected similarities with actual embryos. These clumps, called embryoid bodies, consist of hundreds of cells, many of which begin to form more mature cell types. For example, they often contain groups of primitive … Continue reading Protein found to direct embryonic stem cells as they mature
Genetic Factors Found to Speed Embryonic Stem Cell Division
Researchers at UC, San Francisco developed a novel way of finding out the role of DNA-relatives called microRNA. These molecules are known to turn genes on and off and appear to regulate whether embryonic stem cells remain as stem cells or develop into mature cell types, but learning which genes are controlled by each microRNA … Continue reading Genetic Factors Found to Speed Embryonic Stem Cell Division
Early immune cells created from embryonic stem cells
Researchers at UC, Los Angeles have created cells that go on to form normal T cells out of human embryonic stem cells. What’s more, these cells were grown in the absence of animal feeder cells, which are usually needed to sustain embryonic stem cells. Avoiding potential contamination by such feeder cells is an important step … Continue reading Early immune cells created from embryonic stem cells
Embryonic stem cells repair heart damage in mice
Researchers at the Stanford University School of Medicine found that cells derived from human embryonic stem cells could repair damage in a mouse model of heart attack. The researchers first looked at which genes were active at every stage between the human embryonic stem cells and early heart muscle cells. The cells they implanted mirrored … Continue reading Embryonic stem cells repair heart damage in mice
New Stem Cell Lines Created from Testes Biopsy
Researchers at Stanford University School of Medicine have created new stem cell lines from cells found in the human testes. Like embryonic stem cells, these cell lines are pluripotent, which means that they can form all cell types in the adult body. The work follows similar research finding that adult stem cells in mouse testes … Continue reading New Stem Cell Lines Created from Testes Biopsy
Genetic Profile Distinguishes Types of Stem Cells
Researchers at the The Scripps Research Institute found a new way of classifying the many cell types that fall under the category of “stem cells.” The term stem cell refers to tissue specific stem cells found in mature tissues such as blood, brain, or muscle, which are restricted to forming only cells found in those … Continue reading Genetic Profile Distinguishes Types of Stem Cells
Genetic Factor Influences Heart Muscle Formation from Embryonic Stem Cells
Researchers at the Gladstone Institute for Cardiovascular Disease discovered how two specific tiny genetic factors called microRNAs influence the differentiation of embryonic stem cells into heart muscle. They found that the factors not only drive the versatile cells to become heart, but also actively prevent them from becoming other tissue such as bone adding to … Continue reading Genetic Factor Influences Heart Muscle Formation from Embryonic Stem Cells