Researchers discover how to steer stem cells to regenerate cartilage in joints

Dr. Charles K.F. Chan (Left) and Dr. Michael Longaker (right), Stanford University Cartilage is a flexible, connective tissue in our joints that is important for cushioning our bones against impacts. This cartilage deteriorates as we age due to normal wear and tear and in some instances excessive damage or a deteriorating disease. The deterioration of … Continue reading Researchers discover how to steer stem cells to regenerate cartilage in joints

The Most Important Gift of All

Photo courtesy American Hospital Association There are many players who have a key role in helping make a stem cell therapy work. The scientists who develop the therapy, the medical team who deliver it and funders like CIRM who provide the money to make this all happen. But vital as they are, in some therapies … Continue reading The Most Important Gift of All

Stem cell clinics make big claims but offer little evidence they can treat osteoarthritic knees

If someone says they have a success rate of close to 100 percent in treating a major health problem but offer little evidence to back that up, you might be excused for being more than a tad skeptical. And a new study says you would be right. The health problem in question is osteoarthritis (OA) … Continue reading Stem cell clinics make big claims but offer little evidence they can treat osteoarthritic knees

A shot in the arm for people with bad knees

Almost every day I get an email or phone call from someone asking if we have a stem cell therapy for bad knees. The inquiries are from people who’ve been told they need surgery to replace joints damaged by age and arthritis. They’re not alone. Every year around 600,000 Americans get a knee replacement. That … Continue reading A shot in the arm for people with bad knees

Clever technique uncovers role of stem cells in cartilage repair

Over 50 million adults in the U.S. are estimated to be affected by some form of arthritis, a very painful, debilitating condition in which the cartilage that provides cushioning within bone joints gradually degrades. Health care costs of treating arthritis in California alone has been estimated at over $12 billion and that figure is already … Continue reading Clever technique uncovers role of stem cells in cartilage repair

Translating great stem cell ideas into effective therapies

In science, there are a lot of terms that could easily mystify people without a research background; “translational” is not one of them. Translational research simply means to take findings from basic research and advance them into something that is ready to be tested in people in a clinical trial. Yesterday our Governing Board approved … Continue reading Translating great stem cell ideas into effective therapies

Stem cell agency funds clinical trials in three life-threatening conditions

A year ago the CIRM Board unanimously approved a new Strategic Plan for the stem cell agency. In the plan are some rather ambitious goals, including funding ten new clinical trials in 2016. For much of the last year that has looked very ambitious indeed. But today the Board took a big step towards reaching … Continue reading Stem cell agency funds clinical trials in three life-threatening conditions

Finally a possible use for your excess fat; using it to fix your arthritic knee

One of the most common questions we get asked at CIRM, almost every other day to be honest, is “are there any stem cell treatments for people with arthritis in their knees?” It’s not surprising. This is a problem that plagues millions of Americans and is one of the leading causes of disability in the … Continue reading Finally a possible use for your excess fat; using it to fix your arthritic knee

These Are the Cells You’re Looking for: Scientists Devise New Way to Extract Bone-Making Stem Cells from Fat

Buried within our fat tissue are stashes of stem cells—a hidden reservoir of cells that, if given the right cues, can transform into cells that make up bone, cartilage or fat. These cells therefore represent a much-needed store for regenerative therapies that rebuild bone or cartilage lost to disease or injury. The only problem with … Continue reading These Are the Cells You’re Looking for: Scientists Devise New Way to Extract Bone-Making Stem Cells from Fat