Dr. Stephen Lin, CIRM Senior Science Officer By Dr. Stephen Lin Single-cell. It is the new buzzword in biology. Single-cell biology refers to the in-depth characterization of individual cells in an organ or similar microenvironment. Every organ, like the brain or heart, is composed of thousands to millions of cells. Single-cell biology breaks those organs … Continue reading Scientists develop faster, smarter way to classify tumors using single-cell technology
Genomics
Building a progressive pipeline
Dr. Kelly Shepard By Dr. Kelly Shepard One of our favorite things to do at CIRM is deliver exciting news about CIRM projects. This usually entails discussion of recent discoveries that made headlines, or announcing the launch of a new CIRM-funded clinical trial …. tangible signs of progress towards addressing unmet medical needs through advances … Continue reading Building a progressive pipeline
Meet the people who are changing the future
Kristin MacDonald Every so often you hear a story and your first reaction is “oh, I have to share this with someone, anyone, everyone.” That’s what happened to me the other day. I was talking with Kristin MacDonald, an amazing woman, a fierce patient advocate and someone who took part in a CIRM-funded clinical trial … Continue reading Meet the people who are changing the future
Stem Cell All-Stars, All For You
Dr. Larry Goldstein, UC San Diego It’s not often you get a chance to hear some of the brightest minds around talk about their stem cell research and what it could mean for you, me and everyone else. That’s why we’re delighted to be bringing some of the sharpest tools in the stem cell shed … Continue reading Stem Cell All-Stars, All For You
CIRM supported study of gene silencer blocks ALS degeneration, saves motor function
Dr. Martin Marsala, UC San Diego Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that destroys the nerve cells in the brain and spinal cord. As a result of ALS, the motor neurons that enable bodily movement and muscle control are harmed, which can make it difficult to move, … Continue reading CIRM supported study of gene silencer blocks ALS degeneration, saves motor function
Time and money and advancing stem cell research
The human genome Way back in the 1990’s scientists were hard at work decoding the human genome, trying to map and understand all the genes that make up people. At the time there was a sense of hope, a feeling that once we had decoded the genome, we’d have cures for all sorts of things … Continue reading Time and money and advancing stem cell research
Stem cell model reveals deeper understanding into “ALS resilient” neurons
A descriptive illustration of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. Courtesy of ALS Foundation website. Understanding the basic biology of how a cell functions can be crucial to being able to better understand a disease and unlock a potential approach for a treatment. Stem cells are unique in that they give … Continue reading Stem cell model reveals deeper understanding into “ALS resilient” neurons
Advancing stem cell research in many ways
Speakers at the Alpha Stem Cell Clinics Network Symposium: Photo by Marco Sanchez From Day One CIRM’s goal has been to advance stem cell research in California. We don’t do that just by funding the most promising research -though the 51 clinical trials we have funded to date clearly shows we do that rather well … Continue reading Advancing stem cell research in many ways
CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Illustration courtesy of TED website There has been a lot of conversation surrounding CRISPR-Cas9 in these recent months as well as many sensational news stories. Some of these stories highlight the promise this technology holds, while others emphasize a word of caution. But what exactly does this technology do and how does it work? Here … Continue reading CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Stem cell roundup: summer scientists, fat-blocking cells & recent human evolution
Stem cell photo of the week: high schooler becoming a stem cell pro this summer This summer’s CIRM SPARK Programs, stem cell research internships for high school students, are in full swing. Along with research assignments in top-notch stem cell labs, we’ve asked the students to chronicle their internship experiences through Instagram. And today’s stem … Continue reading Stem cell roundup: summer scientists, fat-blocking cells & recent human evolution