Immuno-oncology is all the rage now in biotech publications, with due cause. It is producing some pretty impressive results in patients who failed other therapies. Most of what gets written about involves strengthening or unlocking the action of one immune cell, the T cell. But our immune systems are armed with many types of ammunition; … Continue reading Three teams empower patients’ immune systems to oust cancer
Cell Type
One man’s story points to hope against a deadly skin cancer
At our May Board meeting a gentleman presented his story, which exemplifies being a patient and patient advocate. His name is Norm Beegun. And this is his story. Norm lives in Los Angeles. In 2002 he went to see his regular doctor, an old high school friend, who suggested that since it had been almost … Continue reading One man’s story points to hope against a deadly skin cancer
CIRM fights cancer: $56 million for 5 clinical trials to vanquish tumors for good
[This is the first of three stories on CIRM’s Cancer Fight that we will post this week. Tomorrow’s will discuss two projects that attack cancer stem cells directly and Thursday's will describe three projects that help our immune system wipe out the traitorous cells.] It’s back—two words we would like to remove from the cancer … Continue reading CIRM fights cancer: $56 million for 5 clinical trials to vanquish tumors for good
Funding a clinical trial for deadly cancer is a no brainer
The beast of cancers For a disease that is supposedly quite rare, glioblastoma seems to be awfully common. I have lost two friends to the deadly brain cancer in the last few years. Talking to colleagues and friends here at CIRM, it’s hard to find anyone who doesn’t know someone who has died of it. … Continue reading Funding a clinical trial for deadly cancer is a no brainer
How Brain Stem Cells Could Stay Forever Young
As we age, so do the cells that make up our bodies. To keep us spry as we get older, our bodies rely on adult stem cells to replace the cells in our tissues and organs. Adult stem cells can only generate cell types specific to the organ or tissue that they live in. For … Continue reading How Brain Stem Cells Could Stay Forever Young
Stem cell stories that caught our eye: new CRISPR fix for sickle cell disease, saving saliva stem cells, jumping genes in iPSCs and lung stem cells.
An end run around sickle cell disease with CRISPR The CRISPR-based gene editing technique has got to be the hottest topic in biomedical research right now. And I sense we’re only at the tip of the iceberg with more applications of the technology popping up almost every week. Just two days ago, researchers at the Dana … Continue reading Stem cell stories that caught our eye: new CRISPR fix for sickle cell disease, saving saliva stem cells, jumping genes in iPSCs and lung stem cells.
The Ogawa-Yamanaka Prize Crowns Its First Stem Cell Champion
A world of dark Imagine if you woke up one day and couldn’t see. Your life would change drastically, and you would have to painfully relearn how to function in a world that heavily relies on sight. While most people don’t lose their sight overnight, many suffer from visual impairments that slowly happen over time. … Continue reading The Ogawa-Yamanaka Prize Crowns Its First Stem Cell Champion
The best scientists always want to know more
Some years ago I was in the Wren Library at Trinity College, Cambridge in England when I noticed a display case with a cloth over it. Being a naturally curious person, downright nosy in fact, I lifted the cloth. In the display case was a first edition of Sir Isaac Newton’s Principia Mathematica and in … Continue reading The best scientists always want to know more
Using satellites to build bigger biceps
There are several ways you can build bigger, stronger muscles. You can take the approach favored by our former Governor, Arnold Schwarzenegger, and pump iron till your biceps are as inflated as a birthday balloon. Or you could follow the lead of a research team we are funding and try to use stem cells to … Continue reading Using satellites to build bigger biceps
Brain Stem Cells in a Dish to the Rescue
The best way to impress your friends at the next party you attend might be to casually mention that scientists can grow miniature brain models in a dish using human stem cells. Sure, that might scare away some people, but when you explain how these tiny brain models can be used to study many different … Continue reading Brain Stem Cells in a Dish to the Rescue