It’s good to have a backup plan Our lungs are amazing things. They take in the air we breathe and move it into our blood so that oxygen can be carried to every part of our body. They’re also surprisingly large. If you were to spread out a lung – and I have no idea … Continue reading Stem Cell Roundup: Backup cells to repair damaged lungs; your unique bowels; and California Cures, 71 ways CIRM is changing the face of medicine
organoids
UC Davis researchers make stem cell-derived mini-brains that contain blood vessels
Growing neurons on a flat petri dish is a great way to study the inner workings of nerve signals in the brain. But I think it's safe to argue that a two-dimensional lawn of cells doesn’t capture all the complexity of our intricate, cauliflower-shaped brains. Then again, cracking open the skulls of living patients is … Continue reading UC Davis researchers make stem cell-derived mini-brains that contain blood vessels
Modeling the Human Brain in 3D
(Image from Pasca Lab, Stanford University) Can you guess what the tiny white balls are in this photo? Here’s a hint: they represent the organ you’re using to answer this question. These are 3D brain organoids grown from human pluripotent stem cells in a culture dish. They act as miniature models of the human brain, … Continue reading Modeling the Human Brain in 3D
Stem cell-derived mini-intestines reveal bacteria’s key role in building up a newborn’s gut
The following factoid may induce an identity crisis for some people but it is true that our bodies carry more microbes than human cells. Some studies in 1970’s estimated the ratio at 10:1 though more recent calculations suggest we’re merely half microbe, half human. Because microbes are much smaller than human cells they make up … Continue reading Stem cell-derived mini-intestines reveal bacteria’s key role in building up a newborn’s gut
Stem cell stories that caught our eye: brains, brains and more brains!
This week we bring you three separate stories about the brain. Two are exciting new advances that use stem cells to understand the brain and the third is plain creepy. Bioengineering better brains. Lab grown mini-brains got an upgrade thanks to a study published this week in Nature Biotechnology. Mini-brains are tiny 3D organs that … Continue reading Stem cell stories that caught our eye: brains, brains and more brains!
One scientist’s quest to understand autism using stem cells
April is National Autism Awareness Month and people and organizations around the world trying to both raise awareness and understand autism, which affects more than 20 million people globally. Autism affects early brain development and causes a wide spectrum of social, mental, physical and emotional symptoms that appear during childhood. Because the symptoms and their … Continue reading One scientist’s quest to understand autism using stem cells
Brain Models Get an Upgrade: 3D Mini-Brains
Every year, companies like Apple, Microsoft and Google work tirelessly to upgrade their computer, software and smartphone technologies to satisfy growing demands for more functionality. Much like these companies, biomedical scientists work tirelessly to improve the research techniques and models they use to understand and treat human disease. Today, I’ll be talking about a cool … Continue reading Brain Models Get an Upgrade: 3D Mini-Brains
UCSF Scientists find molecular link between brain stem cells and Zika Infection
The Zika virus scare came to a head in 2015, prompting the World Health Organization to declare the outbreak a global health emergency earlier this year. From a research standpoint, much of the effort has centered on understanding whether the Zika infection is actually a cause of birth defects like microcephaly and how the virus … Continue reading UCSF Scientists find molecular link between brain stem cells and Zika Infection
Scientists use cotton candy to make artificial blood vessels
Gelatin mold with cotton candy made channels. Cotton candy gets a bad rap. The bright, sugary cloud is known for sending kids into hyperdrive and damaging teeth. Usually found at fairs or stadiums, cotton candy is now showing up in labs as a tool to help scientists build artificial blood vessels for lab‑grown organs. From snack … Continue reading Scientists use cotton candy to make artificial blood vessels
Stem cell stories that caught our eye: watching tumors grow, faster creation of stem cells, reducing spinal cord damage, mini organs
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Video shows tumors growing. A team at the University of Iowa used video to capture breast cancer cells recruiting normal cells to the dark side … Continue reading Stem cell stories that caught our eye: watching tumors grow, faster creation of stem cells, reducing spinal cord damage, mini organs