Identifying a Potential New Stem Cell Treatment for Ovarian Cancer

The California Institute for Regenerative Medicine (CIRM) has awarded $5.3 million to Karen Aboody, MD, of City of Hope for late‑stage preclinical work on a neural stem‑cell‑based treatment for chemo‑resistant metastatic ovarian cancer. About 22,000 women in the U.S. are diagnosed with ovarian cancer each year. More than 70 percent are late‑stage with abdominal metastases, … Continue reading Identifying a Potential New Stem Cell Treatment for Ovarian Cancer

Advancing Clinical Research for a CAR T-Cell Therapy for Systemic Lupus Erythematosus (SLE), Autoimmune Diseases

Symptoms of lupus may include pain or swelling in the joints, extreme fatigue, a butterfly rash on the cheeks and nose, and more. CIRM awarded $7.9 million to Barbara Hickingbottom, MD, of Fate Therapeutics to advance FT819, an iPSC‑derived CD19 CAR T‑cell therapy for systemic lupus erythematosus. SLE is a debilitating autoimmune disease affecting more … Continue reading Advancing Clinical Research for a CAR T-Cell Therapy for Systemic Lupus Erythematosus (SLE), Autoimmune Diseases

CIRM Funds Parkinson’s Disease Research

Stock image of Parkinson's disease nerve cells. The California Institute for Regenerative Medicine (CIRM) approved an $8 million award to Aspen Neuroscience to advance a stem‑cell‑derived dopaminergic neuron therapy for Parkinson’s disease. This personalized therapy is being tested in a first‑in‑human Phase 1/2a trial for people with moderate to advanced PD. More than one million … Continue reading CIRM Funds Parkinson’s Disease Research

Former CIRM Bridges Intern Receives Rising Black Scientist Award

Photo Credit: California State University, San Marcos. Cal State San Marcos student Kevin Brown Jr., a former CIRM Bridges intern, has won the Rising Black Scientist Award from Cell Press, Cell Signaling Technology, and the Elsevier Foundation. Brown was selected from more than 350 applicants across multiple scientific fields. Applicants were asked to share their … Continue reading Former CIRM Bridges Intern Receives Rising Black Scientist Award

CIRM celebrates landmark 100+ clinical trial awards 

Photo credit: Barbara Ries for UCSF, Jaquell Chandler, and OHSU/Christine Torres Hicks  CIRM, California’s Stem Cell Agency, reached a major milestone by funding its 100th clinical trial. At the February ICOC meeting, the board approved five new trials in Parkinson’s disease, autoimmune disorders, cancers, and other conditions, bringing the total to 103. Jon Thomas thanked … Continue reading CIRM celebrates landmark 100+ clinical trial awards 

CIRM Awards $21.3 Million for Shared Labs

Shared resources, including state-of-the art lab equipment and expertise, foster collaboration (above). Photo courtesy of UCLA Broad Stem Cell Research Center.  The California Institute for Regenerative Medicine (CIRM) CIRM has approved $21.3 million to create a network of Shared Resources Laboratories for stem‑cell‑based modeling. These laboratories are a key part of CIRM’s Infrastructure Program, which … Continue reading CIRM Awards $21.3 Million for Shared Labs

CIRM awards more than $56 million for Parkinson’s disease, autoimmune conditions, and cancer research

The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, awarded $56 million to fund various clinical research aimed at treating Parkinson’s disease, autoimmune conditions and a variety of cancers. The awards will support seven projects—five clinical trials and two preclinical projects—in the Agency’s clinical program, which provides funding for … Continue reading CIRM awards more than $56 million for Parkinson’s disease, autoimmune conditions, and cancer research

Neurona Therapeutics Raises $120M Financing, Cell Therapy Shows Positive Outcomes in CIRM-Funded Trial

Photo Courtesy of Neurona Therapeutics/Curtis Myers Neurona Therapeutics, a clinical-stage biotherapeutics company advancing regenerative cell therapy candidates for the treatment of neurological disorders, recently announced the successful completion of a $120 million financing.   Neurona’s financial success is an encouraging sign for the stem cell and gene therapy sector, highlighting partnerships with investors and public organizations … Continue reading Neurona Therapeutics Raises $120M Financing, Cell Therapy Shows Positive Outcomes in CIRM-Funded Trial

CIRM invests $26 million in clinical-stage research, including for bipolar disorder and depression 

Stock image of a dual tone brain by Getty Images The California Institute for Regenerative Medicine (CIRM) awarded nearly $26 million to support clinical research, funding projects that included treatments for bipolar disorder and depression. The awards included funding for advancing a spinal cord injury therapy. These awards support four projects in CIRM’s clinical program. … Continue reading CIRM invests $26 million in clinical-stage research, including for bipolar disorder and depression 

CIRM Announces Interim CEO

Vito Imbasciani, PhD, MD, Board Chair and Jonathan Thomas, PhD, JD, Interim President and CEO South San Francisco, CA, Dec. 15, 2023 - The Independent Citizens Oversight Committee (ICOC), the governing board of the California Institute for Regenerative Medicine (CIRM), named Jonathan Thomas, PhD, JD, as CIRM’s Interim President and CEO at the Dec. 14 meeting. … Continue reading CIRM Announces Interim CEO