Contributed by Wikimedia Commons (Public Domain) Glioblastoma (GBM) is an aggressive form of cancer that begins in the brain and results in tumors that can be very difficult to treat. This condition has claimed the lives of Beau Biden, former Vice President Joe Biden's son, and John McCain, former Senator of Arizona. However, a new … Continue reading New CAR-T cell therapy using scorpion venom developed to treat brain tumors
T-cells
Human immune cells made using pluripotent stem cells in world first
Dr. Andrew Elfanty (left) and Dr. Ed Stanley (right), Murdoch Children's Research Institute in Melbourne, Australia Our immune system is the first line of defense our bodies use to fight off infections and disease. One crucial component of this defense mechanism are lymphocytes, which are specialized cells that give rise to various kinds of immune … Continue reading Human immune cells made using pluripotent stem cells in world first
An off-the-shelf cancer killer
iPS Cell: Photo from the lab of Kathrin Plath at UCLA One of the hottest areas in cancer research right now is the use of CAR-T treatments. These use the patient’s own re-engineered immune system cells to target and kill the tumor. But the thing that makes it so appealing – using the patient’s own … Continue reading An off-the-shelf cancer killer
What is IPEX syndrome? A deeper dive into a CIRM funded award
Brian Lookofsky (left) and his son Taylor Lookofsky (right) at the CIRM Board meeting on October 31, 2019. Taylor is living with IPEX syndrome. Last week we shared a powerful story of patient advocate Taylor Lookofsky, a young man with IPEX syndrome. In his speech, he talked about the impact the condition has had on … Continue reading What is IPEX syndrome? A deeper dive into a CIRM funded award
Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
The governing Board of the California Institute for Regenerative Medicine (CIRM) yesterday invested $32.92 million to fund the Stem Cell Agency’s first clinical trial in Parkinson’s disease (PD), and to support three clinical trials targeting different forms of vision loss. This brings the total number of clinical trials funded by CIRM to 60. The PD … Continue reading Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
UCLA Conducts CAR-T Cell Clinical Trial for Patients with Recurring and Non-Responsive Cancers
Dr. Sarah Larson (left) and Dr. Yvonne Chen (right) There have been many advances made towards the treatment of various cancers, such as deadly forms of leukemia and lymphoma, that were once considered a death sentence and thought to be incurable. Unfortunately, there are still people who do not respond to treatment or eventually relapse … Continue reading UCLA Conducts CAR-T Cell Clinical Trial for Patients with Recurring and Non-Responsive Cancers
Stem cell progress and promise in fighting leukemia
Computer illustration of a cancerous white blood cell in leukemia. There is nothing you can do to prevent or reduce your risk of leukemia. That’s not a very reassuring statement considering that this year alone almost 62,000 Americans will be diagnosed with leukemia; almost 23,000 will die from the disease. That’s why CIRM is funding … Continue reading Stem cell progress and promise in fighting leukemia
CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
Dr. Saul Priceman Yesterday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $9.28 million to Dr. Saul Priceman at City of Hope to conduct a clinical trial for the treatment of breast cancer related brain metastases, which are tumors in the brain that have spread from the original site of the … Continue reading CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
Rare Disease Gets Big Boost from California’s Stem Cell Agency
UC Irvine's Dr. Leslie Thompson and patient advocate Frances Saldana after the CIRM Board vote to approve funding for Huntington's disease If you were looking for a poster child for an unmet medical need Huntington’s disease (HD) would be high on the list. It’s a devastating disease that attacks the brain, steadily destroying the ability … Continue reading Rare Disease Gets Big Boost from California’s Stem Cell Agency
New hope for stem cell therapy in patients with leukemia
Of the many different kinds of cancer that affect humans, leukemia is the most common in young people. As with many types cancer, doctors mostly turn to chemotherapy to treat patients. Chemotherapy, however, comes with its own share of issues, primarily severe side effects and the constant threat of disease recurrence. Stem cell therapy treatment … Continue reading New hope for stem cell therapy in patients with leukemia