COVID-19
UCLA scientists discover how SARS-CoV-2 causes multiple organ failure in mice
Heart muscle cells in an uninfected mouse (left) and a mouse infected with SARS-CoV-2 (right) with mitochondria seen in pink. The disorganization of the cells and mitochondria in the image at right is associated with irregular heartbeat and death. Image credit: UCLA Broad Stem Cell Center As the worldwide coronavirus pandemic rages on, scientists are trying … Continue reading UCLA scientists discover how SARS-CoV-2 causes multiple organ failure in mice
You can’t take it if you don’t make it
Biomedical specialist Mamadou Dialio at work in the Cedars-Sinai Biomanufacturing Center. Photo by Cedars-Sinai. Following the race to develop a vaccine for COVID-19 has been a crash course in learning how complicated creating a new therapy is. It’s not just the science involved, but the logistics. Coming up with a vaccine that is both safe … Continue reading You can’t take it if you don’t make it
CIRM-funded study shows how cigarette smoke can worsen COVID-19 infection in the airways
Microscopic images of human stem cell–derived airway tissue models with cell nuclei (blue) and SARS-CoV-2 virus infected cells (green); tissue exposed to cigarette smoke (right) had 2 to 3 times more infected cells than non-exposed tissue (left).Image Credit: UCLA Broad Stem Cell Research Center/Cell Stem Cell In the middle of a pandemic, stress can run … Continue reading CIRM-funded study shows how cigarette smoke can worsen COVID-19 infection in the airways
One shot, two benefits!
Doctor preparing an influenza vaccine for a patient. To try and boost sales during the pandemic many businesses are offering two-for-one deals; buy one product get another free. Well, that might also be the case with a flu shot; get one jab and get protection from two viruses. A new study offers an intriguing – … Continue reading One shot, two benefits!
Want to help us solve a mystery?
Patient that has recovered from Covid-19 donating blood plasma. Photo courtesy Science Photo Convalescent plasma has been in the news a lot lately as a potential treatment for people infected with the coronavirus. In August the US Food and Drug Administration (FDA) granted emergency use authorization (EUA) to use these products based on preliminary data … Continue reading Want to help us solve a mystery?
‘Mini lung’ model shows scientists early stages of new coronavirus infection
Representative image of three-dimensional human lung alveolar organoid showing alveolar stem cell marker, HTII-280 (red) and SARS-CoV-2 entry protein, ACE2 (green) Image Credit: Jeonghwan Youk, Taewoo Kim, and Seon Pyo Hong The development of organoid modeling has significantly expanded our understanding of human organs and the diseases that can affect them. For those unfamiliar with … Continue reading ‘Mini lung’ model shows scientists early stages of new coronavirus infection
An Atlas of the Human Heart that May Guide Development of New Therapies
By Lisa Kadyk, PhD. CIRM Senior Science Officer Illustration of a man's heart - Courtesy Science Photo I love maps; I still have auto club maps of various parts of the country in my car. But, to tell the truth, those maps just don’t have as much information as I can get by typing in … Continue reading An Atlas of the Human Heart that May Guide Development of New Therapies
Battling COVID and turning back the clock on stem cell funding
Coronavirus Battling the virus that causes COVID-19 is something that is top of everyone’s mind right now. That’s why CIRM is funding 17 different projects targeting the virus. But one of the most valuable tools in helping develop vaccines against a wide variety of diseases in the past is now coming under threat. We’ll talk … Continue reading Battling COVID and turning back the clock on stem cell funding
Exploring tough questions, looking for answers
COVID-19 and social and racial injustice are two of the biggest challenges facing the US right now. This Thursday, October 8th, we are holding a conversation that explores finding answers to both. The CIRM Alpha Stem Cell Clinic Network Symposium is going to feature presentations about advances in stem cell and regenerative research, highlighting treatments … Continue reading Exploring tough questions, looking for answers