Alzheimer's is a progressive disease that destroys memory and other important mental functions. According to the non-profit HFC, co-founded by CIRM Board member Lauren Miller Rogen and her husband Seth Rogen, more than 5 million Americans are living with Alzheimer's. It is the 6th leading cause of death in the U.S. By 2050 as many … Continue reading City of Hope scientists use stem cells to develop ‘mini-brains’ to study Alzheimer’s and to test drugs in development
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Rare disease meeting at California Capitol stresses importance of advocacy, funding, and new research
Dr. Martin Cadeiras (far left), who specializes in cardiovascular medicine at UC Davis, discusses the rare disease amyloidosis. Next to Dr. Cadeiras is Len Strickland, a patient advocates who shares his perspective on living with the disease. "By changing policy, we can change lives" A powerful opening statement by Angela Ramirez Holmes, Founder & President … Continue reading Rare disease meeting at California Capitol stresses importance of advocacy, funding, and new research
CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Dr. Mathew Blurton-Jones, leader of team that developed the chimeric "Mighty Mouse" model at the University of California, Irvine In ancient Greek mythology, a Chimera was a creature that was usually depicted as a lion with an additional goat head and a serpent for a tail. Due to the Chimera's animal hybrid nature, the term … Continue reading CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Gladstone researchers tame toxic protein that carries increased Alzheimer’s risk
With a clinical trial failure rate of 99% over the past 15 years or so, the path to a cure for Alzheimer’s disease is riddled with disappointment. In many cases, candidate therapies looked very promising in pre-clinical animal studies, only to flop when tested in people. Now, a CIRM-funded Nature Medicine study by researchers at … Continue reading Gladstone researchers tame toxic protein that carries increased Alzheimer’s risk
Alzheimer’s and the Inflamed Brain: Their Links Run Deeper than Thought
Given that Alzheimer’s disease (AD) is a brain disorder and the leading cause of dementia, it seems logical to assume that some sort of breakdown in the connections of the brain’s nerve cells is mostly to blame. But based on an increasing volume of research, it turns out that our immune system is also closely … Continue reading Alzheimer’s and the Inflamed Brain: Their Links Run Deeper than Thought