Old therapies inspire new hope for treatment of pediatric brain tumors

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST A recent study led by John Hopkins Medicine has found that combining two ‘old therapies’ can offer a surprising new purpose – fighting Medulloblastoma, the most common malignant brain tumor in children. The fast-growing cancerous tumor originates in the brain or spinal cord and has traditionally been … Continue reading Old therapies inspire new hope for treatment of pediatric brain tumors

CIRM Board Approves Clinical Trials for Blood Cancer and Pediatric Brain Tumors

Today the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $14.4 million for two new clinical trials for blood cancer and pediatric brain tumors. These awards bring the total number of CIRM-funded clinical trials to 70.  $6.0 million was awarded to Immune-Onc Therapeutics to conduct a clinical trial for patients with acute … Continue reading CIRM Board Approves Clinical Trials for Blood Cancer and Pediatric Brain Tumors

Two studies identify a molecule that could be used to block Zika virus and kill cancer cells

Zika virus is caused by a virus transmitted by Aedes mosquitoes. People usually develop mild symptoms that include fever, rash, and muscle and joint pain. However, Zika virus infection during pregnancy can lead to much more serious problems. The virus causes infants to be born with microcephaly, a condition in which the brain does not … Continue reading Two studies identify a molecule that could be used to block Zika virus and kill cancer cells

Drug used to treat multiple sclerosis may improve glioblastoma outcomes

Glioblastoma is an aggressive form of cancer that invades brain tissue, making it extremely difficult to treat. Current therapies involving radiation and chemotherapy are effective in destroying the bulk of brain cancer cells, but they are not able to reach the brain cancer stem cells, which have the ability to grow and multiply indefinitely. These … Continue reading Drug used to treat multiple sclerosis may improve glioblastoma outcomes

Scientists develop faster, smarter way to classify tumors using single-cell technology

By Dr. Stephen Lin Single-cell.  It is the new buzzword in biology.  Single-cell biology refers to the in-depth characterization of individual cells in an organ or similar microenvironment.  Every organ, like the brain or heart, is composed of thousands to millions of cells.  Single-cell biology breaks those organs down into their individual cell components to … Continue reading Scientists develop faster, smarter way to classify tumors using single-cell technology

City of Hope researchers discover potential therapy to treat brain tumors

Glioblastoma (GBM) is a common type of aggressive brain tumor that is found in adults.  Survival of this type of brain cancer is poor with just 40% survival in the first-year post diagnosis and 17% in the second year, according to the American Association of Neurological Surgeons.  This disease has taken the life of former … Continue reading City of Hope researchers discover potential therapy to treat brain tumors

CIRM Board invests in new approaches to brain cancer and Parkinson’s disease

Parkinson’s disease and glioblastoma are very different diseases of the brain but neither has very good treatment options and both clearly represent an unmet medical need. With that in mind, the governing Board of the California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, yesterday voted to invest almost $9.5 million in developing … Continue reading CIRM Board invests in new approaches to brain cancer and Parkinson’s disease

New model unlocks clues to treating deadly childhood cancer

CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be used to help children battling a deadly brain cancer. The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of the brain … Continue reading New model unlocks clues to treating deadly childhood cancer

Taking a new approach to fighting a deadly brain cancer

CIRM’s 2017 Annual Report will be going live online very soon. In anticipation of that we are highlighting some of the key elements from the report here on the Stem Cellar. One of the most exciting new approaches in targeting deadly cancers is chimeric antigen receptor (CAR) T-cell therapy, using the patient’s own immune system … Continue reading Taking a new approach to fighting a deadly brain cancer