CIRM Board Approves New Clinical Trial for ALS

This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $11.99 million to Cedars-Sinai to fund a clinical trial for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.  ALS is a neurodegenerative disease that results in the death of nerve cells in the brain and spinal cord, causing … Continue reading CIRM Board Approves New Clinical Trial for ALS

U.C. San Diego Scientist Larry Goldstein Joins Stem Cell Agency’s Board

Larry Goldstein PhD, has many titles, one of which sums up his career perfectly, “Distinguished Professor”. Dr. Goldstein has distinguished himself on many fronts, making him an ideal addition to the governing Board of the California Institute for Regenerative Medicine (CIRM). Dr. Goldstein – everyone calls him Larry – is a Cell Biologist, Geneticist and … Continue reading U.C. San Diego Scientist Larry Goldstein Joins Stem Cell Agency’s Board

CIRM Board Meeting Highlights Important Updates to Clinical Trials

This past Thursday the governing Board of the California Institute for Regenerative Medicine (CIRM) were presented with an update on CIRM’s clinical portfolio, which to date includes 60 clinical trials in various areas including kidney failure, cancer, and other rare diseases.  The full President’s Report gives an update on 15 of these trials, in addition … Continue reading CIRM Board Meeting Highlights Important Updates to Clinical Trials

CIRM supported study of gene silencer blocks ALS degeneration, saves motor function

Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is a neurodegenerative disease that destroys the nerve cells in the brain and spinal cord. As a result of ALS, the motor neurons that enable bodily movement and muscle control are harmed, which can make it difficult to move, speak, eat, and breathe. This condition … Continue reading CIRM supported study of gene silencer blocks ALS degeneration, saves motor function

What to be thankful for this Thanksgiving: scientists hard at work

With Thanksgiving and Black Friday approaching in the next couple of days, we wanted to give thanks to all the scientists hard at work during this holiday weekend. Science does not sleep–the groundbreaking research and experiments that are being conducted do not take days off. There are tasks in the laboratory that need to be … Continue reading What to be thankful for this Thanksgiving: scientists hard at work

Regulated, reputable, and reliable – distinguishing legitimate clinical trials from predatory clinics

Here at CIRM, we get calls every day from patients asking us if there are any trials or therapies available to treat their illness or an illness affecting a loved one. Unfortunately, there are some predatory clinics that try to take advantage of this desperation by advertising unproven and unregulated treatments for a wide range … Continue reading Regulated, reputable, and reliable – distinguishing legitimate clinical trials from predatory clinics

Blood-brain barrier chip created with stem cells expands potential for personalized medicine

The brain is a complex part of the human body that allows for the formation of thoughts and consciousness. In many ways it is the essence of who we are as individuals. Because of its importance, our bodies have developed various layers of protection around this vital organ, one of which is called the blood-brain … Continue reading Blood-brain barrier chip created with stem cells expands potential for personalized medicine

Stem cell model reveals deeper understanding into “ALS resilient” neurons

Understanding the basic biology of how a cell functions can be crucial to being able to better understand a disease and unlock a potential approach for a treatment. Stem cells are unique in that they give scientists the opportunity to create a controlled environment of cells that might be otherwise difficult to study. Dr. Eva … Continue reading Stem cell model reveals deeper understanding into “ALS resilient” neurons

Organoids revolutionize approach to studying a variety of diseases

There are limitations to studying cells under a microscope. To understand some of the more complex processes, it is critical to see how these cells behave in an environment that is similar to conditions in the body. The production of organoids has revolutionized this approach. Organoids are three-dimensional structures derived from stem cells that have … Continue reading Organoids revolutionize approach to studying a variety of diseases