CIRM-funded stem cell-gene therapy shows promise in ALS safety trial

With funding support from the California Institute for Regenerative Medicine (CIRM), Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons in the spinal cord of patients with amyotrophic lateral … Continue reading CIRM-funded stem cell-gene therapy shows promise in ALS safety trial

CIRM Board Approves New Clinical Trial for ALS

This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $11.99 million to Cedars-Sinai to fund a clinical trial for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.  ALS is a neurodegenerative disease that results in the death of nerve cells in the brain and spinal cord, causing … Continue reading CIRM Board Approves New Clinical Trial for ALS

A step forward in finding a treatment for a deadly neurological disorder

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a nasty disease that steadily attacks nerve cells in the brain and spinal cord. It’s pretty much always fatal within a few years. As if that wasn’t bad enough, ALS also can overlap with a … Continue reading A step forward in finding a treatment for a deadly neurological disorder

CIRM supported study of gene silencer blocks ALS degeneration, saves motor function

Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is a neurodegenerative disease that destroys the nerve cells in the brain and spinal cord. As a result of ALS, the motor neurons that enable bodily movement and muscle control are harmed, which can make it difficult to move, speak, eat, and breathe. This condition … Continue reading CIRM supported study of gene silencer blocks ALS degeneration, saves motor function

The Most Read Stem Cellar Blog Posts of 2021

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST This year was a momentous one for the California Institute for Regenerative Medicine (CIRM). We celebrated the passage of Proposition 14, and as a result, introduced our new strategic plan and added a group of talented individuals to our team.   We shared our most exciting updates and newsworthy stories—topics ranging from stem cell research to diversity … Continue reading The Most Read Stem Cellar Blog Posts of 2021

U.C. San Diego Scientist Larry Goldstein Joins Stem Cell Agency’s Board

Larry Goldstein PhD, has many titles, one of which sums up his career perfectly, “Distinguished Professor”. Dr. Goldstein has distinguished himself on many fronts, making him an ideal addition to the governing Board of the California Institute for Regenerative Medicine (CIRM). Dr. Goldstein – everyone calls him Larry – is a Cell Biologist, Geneticist and … Continue reading U.C. San Diego Scientist Larry Goldstein Joins Stem Cell Agency’s Board

Stem cell model reveals deeper understanding into “ALS resilient” neurons

Understanding the basic biology of how a cell functions can be crucial to being able to better understand a disease and unlock a potential approach for a treatment. Stem cells are unique in that they give scientists the opportunity to create a controlled environment of cells that might be otherwise difficult to study. Dr. Eva … Continue reading Stem cell model reveals deeper understanding into “ALS resilient” neurons

CIRM Board Meeting Highlights Important Updates to Clinical Trials

This past Thursday the governing Board of the California Institute for Regenerative Medicine (CIRM) were presented with an update on CIRM’s clinical portfolio, which to date includes 60 clinical trials in various areas including kidney failure, cancer, and other rare diseases.  The full President’s Report gives an update on 15 of these trials, in addition … Continue reading CIRM Board Meeting Highlights Important Updates to Clinical Trials