Researchers find connection between aging muscles and mutations in stem cells

It’s a humbling fact of life that our muscles decline as we age which is why you didn’t see any 50-year-olds competing for Olympic Gold in figure skating at the 2018 Winter Games. You can blame your muscle stem cells for this. Also called satellite cells, these adult stem cells lie mostly dormant in muscle … Continue reading Researchers find connection between aging muscles and mutations in stem cells

The life of a sleeping muscle stem cell is very busy

For biological processes, knowing when to slow down is as important as knowing when to step on the accelerator. Take for example muscle stem cells. In a healthy state, these cells mostly lay quiet and rarely divide but upon injury, they bolt into action by dividing and specializing into new muscle cells to help repair … Continue reading The life of a sleeping muscle stem cell is very busy

Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?

Skin stem cells specialize into new skin by sensing neighborhood crowding When embarking on a road trip, the GPS technology inside our smartphones helps us know where we are and how to get where we’re going. The stem cells buried in the deepest layers of our skin don’t have a GPS and yet, they do … Continue reading Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?

An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration

We’ve written many blogs over the years about research focused on muscle stem cell function . Those stories describe how satellite cells, another name for muscle stem cells, lay dormant but jump into action to grow new muscle cells in response to injury and damage. And when satellite function breaks down with aging as well as … Continue reading An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration

Scientists find new stem cell target for regenerating aging muscles

Today I’m going to use our former governor Arnold Schwarzenegger as an example of what happens to our muscles when we age. One of Arnold’s many talents when he was younger was being a professional bodybuilder. As you can see in this photo, Arnold worked hard to generate an impressive amount of muscle that landed … Continue reading Scientists find new stem cell target for regenerating aging muscles

CIRM-Funded Scientists Test Recipe for Building New Muscles

When muscles get damaged due to disease or injury, the body activates its reserves—muscle stem cells that head to the injury site and mature into fully functioning muscle cells. But when the reserves are all used up, things get tricky. This is especially the case for people living with muscle diseases, such as muscular dystrophy, … Continue reading CIRM-Funded Scientists Test Recipe for Building New Muscles

Young stem cells’ DNA has more genes switched to “on” position than geriatric ones

Skeletal muscle courtesy of Wikimedia Commons Researchers at Stanford University have made a start in understanding why muscles in younger people heal so quickly compared to muscles in older people. Understanding these differences could help scientists find ways of helping muscles in older people heal more quickly after injuries. In a study comparing muscle stem … Continue reading Young stem cells’ DNA has more genes switched to “on” position than geriatric ones